Human Mutant Dynactin Subunit 1 Causes Profound Motor Neuron Disease Consistent with Possible Mechanisms Involving Axonopathy, Mitochondriopathy, Protein Nitration, and T-Cell-Mediated Cytolysis Article

Xie, Victor, Franco, Maria Clara, Martin, Lee J. (2025). Human Mutant Dynactin Subunit 1 Causes Profound Motor Neuron Disease Consistent with Possible Mechanisms Involving Axonopathy, Mitochondriopathy, Protein Nitration, and T-Cell-Mediated Cytolysis . 15(12), 1637. 10.3390/biom15121637

cited authors

  • Xie, Victor; Franco, Maria Clara; Martin, Lee J

authors

publication date

  • November 21, 2025

keywords

  • 2.1 Biological and endogenous factors
  • 31 Biological Sciences
  • 3101 Biochemistry and Cell Biology
  • 5.1 Pharmaceuticals
  • Brain Disorders
  • Genetics
  • Neurodegenerative
  • Neurological
  • Neurosciences
  • Orphan Drug
  • Rare Diseases

Digital Object Identifier (DOI)

publisher

  • MDPI

start page

  • 1637

volume

  • 15

issue

  • 12