Amyloid-β plaque-associated microglia drive TSPO upregulation in Alzheimer's disease Article

Martinez-Perez, Daniel A, McGlothan, Jennifer L, Rodichkin, Alexander N et al. (2025). Amyloid-β plaque-associated microglia drive TSPO upregulation in Alzheimer's disease . 150(1), 10.1007/s00401-025-02912-4

Open Access International Collaboration

cited authors

  • Martinez-Perez, Daniel A; McGlothan, Jennifer L; Rodichkin, Alexander N; Abilmouna, Karam; Bursac, Zoran; Lopera, Francisco; Villegas-Lanau, Carlos Andres; Guilarte, Tomas R

sustainable development goals

authors

publication date

  • July 17, 2025

keywords

  • 5XFAD mice
  • PSEN1-E280A mutation
  • ACTIVATION
  • AFFINITY BINDING
  • Alzheimer's disease
  • BRAIN
  • C-11 PBR28
  • Clinical Neurology
  • DEPOSITION
  • GLUCOSE-METABOLISM
  • Life Sciences & Biomedicine
  • MOUSE MODEL
  • Microglia
  • NEUROINFLAMMATION
  • Neuroinflammation
  • Neurosciences
  • Neurosciences & Neurology
  • PET
  • PROTEIN 18 KDA
  • Pathology
  • Science & Technology
  • TSPO

Digital Object Identifier (DOI)

publisher

  • SPRINGER

volume

  • 150

issue

  • 1